Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839629 | 0.84 | CA12 (0.41) | ALDH1A1HPGDKMT2ANPC1RAB9A | |
| SCHEMBL13839632 | 0.83 | MAOA (0.33) | MAOAMAOB | |
| SCHEMBL13839621 | 0.81 | CYP1A2 (0.34) | ALDH1A1MAOAMAOBCYP2D6SMN1; SMN2 | |
| SCHEMBL13839636 | 0.81 | NISCH (0.33) | ALDH1A1HPGDMAOAMAOBSLC6A2 | |
| SCHEMBL13839626 | 0.80 | HTR1B (0.35) | ALDH1A1HPGDSLC6A2SLC6A4KMT2A | |
| SCHEMBL13839620 | 0.79 | HRH1 (0.35) | RAB9A | |
| SCHEMBL13839630 | 0.78 | KDM4E (0.37) | MAOAMAOB | |
| SCHEMBL13841317 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HPGDMAOAMAOBKMT2A | |
| SCHEMBL215848 | 0.77 | TSHR (0.46) | ALDH1A1GLAHPGDSLC6A2SLC6A4 | |
| SCHEMBL29405565 | 0.77 | TSHR (0.46) | ALDH1A1GLAHPGDSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |