SCHEMBL13839632

SCHEMBL13839632

c1ccc(OP(Oc2ccccc2)Oc2cccc3c2Oc2c(cccc2OP(Oc2ccccc2)Oc2ccccc2)C3)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13839620 0.83 HRH1 (0.35)
SCHEMBL13839631 0.83 LMNA (0.37)
SCHEMBL13839629 0.83 CA12 (0.41)
SCHEMBL13839619 0.83 ALDH1A1 (0.35) MAOAMAOB
SCHEMBL13839626 0.81 HTR1B (0.35)
SCHEMBL13839621 0.79 CYP1A2 (0.34) MAOAMAOBCNR2
SCHEMBL13839636 0.79 NISCH (0.33) MAOAMAOB
SCHEMBL13841317 0.79 ALDH1A1 (0.40) MAOAMAOB
SCHEMBL13839630 0.79 KDM4E (0.37) MAOAMAOB
SCHEMBL13839641 0.77 HTR2A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531682-B2 Method for making nitrile compounds from ethylenically unsaturated compounds RHODIA POLYAMIDE INTERMEDIATES (FR) 2009-05-12 US disclosed
US-7531682-B2 Method for making nitrile compounds from ethylenically unsaturated compounds RHODIA POLYAMIDE INTERMEDIATES (FR) 2009-05-12 US disclosed
US-7253298-B2 Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization RHODIA POLYAMIDE INTERMEDIATES (FR) 2007-08-07 US disclosed
US-7253298-B2 Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization RHODIA POLYAMIDE INTERMEDIATES (FR) 2007-08-07 US disclosed