Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839646 | 0.87 | LMNA (0.44) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL13839642 | 0.81 | POLB (0.44) | ALDH1A1HTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL13839653 | 0.81 | KMT2A (0.47) | ALDH1A1HTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL13839657 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL2861909 | 0.79 | GABRA1 (0.43) | ALDH1A1L3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL29636737 | 0.79 | GABRA1 (0.43) | ALDH1A1L3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL134288 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL13839644 | 0.77 | NPSR1 (0.51) | ALDH1A1HTTPOLBNPSR1KMT2A | |
| SCHEMBL13839643 | 0.77 | HTT (0.43) | ALDH1A1HTTPOLBNPSR1L3MBTL1 | |
| SCHEMBL13839650 | 0.76 | ALDH1A1 (0.40) | ALDH1A1HTTPOLBNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7531682-B2 | Method for making nitrile compounds from ethylenically unsaturated compounds | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2009-05-12 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |
| US-7253298-B2 | Hydrocyanating an unsaturated aliphatic nitrile, or a linear pentenenitrile in a liquid medium with hydrogen cyanide in the presence of a Nickel catalyst with an triaryl phosphite ligand; isomerization | RHODIA POLYAMIDE INTERMEDIATES (FR) | 2007-08-07 | — | — | US | disclosed |