Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 6/20 | 0.51 |
| ▸ | MTTP | P55157 | 13/20 | 0.48 |
| ▸ | APOB | P04114 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839969 | 0.95 | NPY2R (0.48) | NPY2RMTTPAPOB | |
| SCHEMBL13839916 | 0.94 | NPY2R (0.53) | NPY2RMTTPAPOB | |
| SCHEMBL13839854 | 0.92 | NPY2R (0.60) | NPY2RMTTP | |
| SCHEMBL13839906 | 0.91 | NPY2R (0.62) | NPY2RMTTPAPOB | |
| SCHEMBL13839958 | 0.89 | NPY2R (0.49) | NPY2RMTTPAPOB | |
| SCHEMBL13839962 | 0.89 | NPY2R (0.49) | NPY2RMTTP | |
| SCHEMBL13839939 | 0.88 | MTTP (0.59) | NPY2RMTTPAPOB | |
| SCHEMBL12174384 | 0.88 | NPY2R (0.69) | NPY2RMTTP | |
| SCHEMBL13839931 | 0.88 | NPY2R (0.58) | NPY2RMTTPAPOB | |
| SCHEMBL13839895 | 0.87 | NPY2R (0.56) | NPY2RMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538124-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-26 | — | — | US | disclosed |
| US-7538124-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-26 | — | — | US | disclosed |
| US-20080275087-A1 | BIPHENYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | MEERPOEL LIEVEN | 2008-11-06 | — | — | US | disclosed |
| US-20080275087-A1 | BIPHENYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | MEERPOEL LIEVEN | 2008-11-06 | — | — | US | disclosed |
| US-7405307-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-29 | — | — | US | disclosed |
| US-20080009522-A1 | BIPHENYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | MEERPOEL LIEVEN | 2008-01-10 | — | — | US | disclosed |
| US-7304167-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-04 | — | — | US | disclosed |
| US-7304167-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-04 | — | — | US | disclosed |
| US-7244848-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-17 | — | — | US | disclosed |
| US-7244848-B2 | Biphenylcarboxamides useful as lipid lowering agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009522-A1 | BIPHENYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | LIPC, PNLIP, FABP4 | NPY2R 1732/4885MTTP 22/4885APOB 13/4885 |
| US-20080275087-A1 | BIPHENYLCARBOXAMIDES USEFUL AS LIPID LOWERING AGENTS | LIPC, PNLIP, FABP4 | NPY2R 1732/4885MTTP 22/4885APOB 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.