Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 4/20 | 0.41 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3918580 | 1.00 | ADRB2 (0.45) | ADRB2ADRB1MAPTSNCAIL1B | |
| SCHEMBL13840706 | 0.90 | PARP1 (0.46) | ADRB2ADRB1MAPT | |
| SCHEMBL3914423 | 0.90 | PARP1 (0.46) | ADRB2ADRB1MAPT | |
| SCHEMBL5968693 | 0.88 | ADRB2 (0.57) | ADRB2ADRB1 | |
| SCHEMBL5968689 | 0.88 | ADRB2 (0.57) | ADRB2ADRB1 | |
| SCHEMBL3924678 | 0.88 | PARP1 (0.44) | ADRB2ADRB1SNCA | |
| SCHEMBL13840701 | 0.88 | PARP1 (0.44) | ADRB2ADRB1SNCA | |
| SCHEMBL13840801 | 0.85 | ADRB2 (0.50) | ADRB2ADRB1 | |
| SCHEMBL3922009 | 0.85 | ADRB2 (0.50) | ADRB2ADRB1 | |
| SCHEMBL3917066 | 0.84 | NPC1 (0.47) | ADRB2ADRB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |