Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.57 |
| ▸ | WDR5 | P61964 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915709 | 1.00 | ADRB2 (0.57) | ADRB2WDR5ADRB1LMNAMEN1 | |
| SCHEMBL3924003 | 0.91 | ADRB2 (0.49) | ADRB2ADRB1LMNAMEN1ALDH1A1 | |
| SCHEMBL13840715 | 0.91 | ADRB2 (0.49) | ADRB2ADRB1LMNAMEN1ALDH1A1 | |
| SCHEMBL3912520 | 0.87 | ADRB2 (0.72) | ADRB2WDR5ADRB1 | |
| SCHEMBL13840710 | 0.87 | ADRB2 (0.72) | ADRB2WDR5ADRB1 | |
| SCHEMBL13840696 | 0.84 | NPC1 (0.47) | ADRB2ADRB1ALDH1A1 | |
| SCHEMBL3917066 | 0.84 | NPC1 (0.47) | ADRB2ADRB1ALDH1A1 | |
| SCHEMBL3914423 | 0.83 | PARP1 (0.46) | ADRB2ADRB1 | |
| SCHEMBL13840706 | 0.83 | PARP1 (0.46) | ADRB2ADRB1 | |
| SCHEMBL4390121 | 0.81 | ADRB2 (0.59) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |
| US-7538141-B2 | Compounds for the treatment of diseases | PFIZER INC. | 2009-05-26 | — | — | US | disclosed |