Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20233630 | 0.93 | KMT2A (0.47) | ABCB1NPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL19990164 | 0.81 | HTT (0.46) | ABCB1NPC1MMP1ALDH1A1KDM4E | |
| SCHEMBL19990163 | 0.81 | HTT (0.46) | ABCB1NPC1MMP1ALDH1A1KDM4E | |
| SCHEMBL3895456 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2AMMP9MMP14 | |
| SCHEMBL13839552 | 0.79 | TSHR (0.47) | ALDH1A1KDM4EKMT2ASLC1A1TSHR | |
| SCHEMBL3883464 | 0.79 | TSHR (0.47) | ALDH1A1KDM4EKMT2ASLC1A1TSHR | |
| SCHEMBL4433529 | 0.79 | SLC1A1 (0.49) | NPC1ALDH1A1MAOBKMT2AMMP9 | |
| SCHEMBL4433522 | 0.79 | SLC1A1 (0.49) | NPC1ALDH1A1MAOBKMT2AMMP9 | |
| SCHEMBL27710469 | 0.78 | KDM4E (0.49) | ALDH1A1KDM4ELMNAKMT2AMMP9 | |
| SCHEMBL7423196 | 0.78 | CA1 (0.57) | ABCB1NPC1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534777-B2 | Des-C,D analogs of 1α,25-dihydroxy-19-norvitamin D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-20070112077-A1 | Des-C,D analogs of 1alpha,25-dihydroxy-19-norvitamin D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-05-17 | — | — | US | disclosed |
| WO-2007028000-A2 | DES-C,D ANALOGS OF 1ALPHA,25-DIHYDROXY-19-NORVITAMIN D3 | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112077-A1 | Des-C,D analogs of 1alpha,25-dihydroxy-19-norvitamin D3 | CYP24A1, VDR, CYP2R1 | ABCB1 3285/4885NPC1 2184/4885MMP1 3931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.