Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 14/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 14/20 | 0.62 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207184 | 0.95 | ADRB2 (0.68) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL9463876 | 0.87 | ADRB2 (0.73) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL4983780 | 0.87 | ADRB2 (0.55) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL6917173 | 0.82 | MAPT (0.53) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL20306721 | 0.82 | ADRB2 (0.59) | ADRB2ADRB1ADRB3SLC1A5RAB9A | |
| SCHEMBL22340408 | 0.81 | ADRB2 (0.58) | ADRB2ADRB1ADRB3ALDH1A1MAPT | |
| SCHEMBL2788016 | 0.80 | MAPT (0.58) | ADRB2ADRB1ADRB3SLC1A5ALDH1A1 | |
| SCHEMBL11470348 | 0.80 | ADRB2 (0.65) | ADRB2ADRB1ADRB3RAB9AALDH1A1 | |
| SCHEMBL13291799 | 0.80 | TDP1 (0.53) | ADRB2ADRB1ADRB3RAB9ANPC1 | |
| SCHEMBL18124421 | 0.80 | ALDH1A1 (0.67) | ADRB2ADRB1ADRB3RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534474-B2 | Multireactive polymerizable mesogenic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-05-19 | — | — | US | disclosed |
| US-20070009675-A1 | Multireactive polymerizable mesogenic compounds | FARRAND LOUISE | 2007-01-11 | — | — | US | disclosed |