Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28860063 | 0.86 | SMN1; SMN2 (0.60) | ALDH1A1MAPTHTTKDM4EKMT2A | |
| SCHEMBL18024801 | 0.86 | HPGD (0.61) | ALDH1A1MAPTHTTKDM4EKMT2A | |
| SCHEMBL27903153 | 0.86 | MAPT (0.52) | ALDH1A1MAPTHTTKDM4EKMT2A | |
| SCHEMBL15631002 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTKDM4EKMT2A | |
| SCHEMBL15574696 | 0.83 | KMT2A (0.53) | ALDH1A1MAPTHTTKDM4EKMT2A | |
| SCHEMBL7597169 | 0.83 | MAPT (0.67) | MAPTKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL7598689 | 0.82 | KMT2A (0.67) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL9055143 | 0.82 | LMNA (0.59) | ALDH1A1MAPTHTTKDM4EKMT2A | |
| SCHEMBL10554702 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL6036200 | 0.80 | KMT2A (0.48) | ALDH1A1MAPTHTTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058919-A1 | CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |