Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13844251 | 0.85 | ALDH1A1 (0.38) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL13924017 | 0.80 | KDM4E (0.55) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL13844238 | 0.79 | ALDH1A1 (0.34) | ALDH1A1USP2CYP3A4TSHRATM | |
| SCHEMBL10005231 | 0.79 | KDM4E (0.64) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL13844362 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1USP2ALOX15LMNA | |
| SCHEMBL24319163 | 0.77 | KDM4E (0.48) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL24319450 | 0.77 | KDM4E (0.48) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL21477194 | 0.77 | KDM4E (0.57) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL21477058 | 0.77 | KDM4E (0.57) | KDM4EGLAALDH1A1USP2ALOX15 | |
| SCHEMBL20214875 | 0.76 | CHRM2 (0.51) | KDM4EGLAALDH1A1USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1702913-B1 | Blowing catalyst compositions containing hydroxyl and surface active groups for the production of polyurethane foams | AIR PROD & CHEM (US) | 2009-05-13 | — | — | EP | disclosed |
| US-7495131-B2 | Blowing catalyst compositions containing hydroxyl and surface active groups for the production of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-02-24 | — | — | US | disclosed |
| US-7495131-B2 | Blowing catalyst compositions containing hydroxyl and surface active groups for the production of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-02-24 | — | — | US | disclosed |