Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976971 | 0.77 | MEN1 (0.74) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL976186 | 0.72 | MEN1 (0.65) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL17637656 | 0.71 | L3MBTL1 (0.35) | KMT2ALMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL976960 | 0.67 | MEN1 (0.61) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL19413677 | 0.67 | L3MBTL1 (0.54) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL24381707 | 0.65 | NPC1 (0.40) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11738224 | 0.64 | MEN1 (0.70) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL21507729 | 0.64 | MAPT (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6016478 | 0.63 | MEN1 (0.69) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL22109693 | 0.63 | ALDH1A1 (0.43) | KMT2ALMNAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055917-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2009-05-07 | — | — | WO | disclosed |