SCHEMBL13845252

SCHEMBL13845252

CC(C)(C)OC(=O)Oc1ccc(-c2ccc(C=O)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.58
KMT2A Q03164 5/20 0.46
KDM1A O60341 1/20 0.44
DRD1 P21728 2/20 0.44
ALDH1A1 P00352 5/20 0.43
CYP2A6 P11509 1/20 0.43
ALDH1A3 P47895 1/20 0.40
KDM4E B2RXH2 3/20 0.39
MAPT P10636 2/20 0.39
PARP10 Q53GL7 1/20 0.39
PARP3 Q9Y6F1 1/20 0.39
STS P08842 1/20 0.39
OGA O60502 1/20 0.38
CA2 P00918 1/20 0.38
HSD17B10 Q99714 1/20 0.37
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2761992 0.95 ELANE (0.64) ELANEKMT2AKDM1AALDH1A1CYP2A6
SCHEMBL4059798 0.88 ELANE (0.72) ELANEKMT2AKDM1ACA2HSD17B10
SCHEMBL9313716 0.85 ELANE (0.53) ELANEKMT2AKDM1AALDH1A1CYP2A6
SCHEMBL978959 0.83 ELANE (0.66) ELANEKMT2AKDM1AMAPTCA2
SCHEMBL919670 0.83 ELANE (0.66) ELANEKMT2AKDM1AMAPTCA2
SCHEMBL7708633 0.83 ELANE (0.66) ELANEKMT2AKDM1AALDH1A1KDM4E
SCHEMBL4061370 0.82 ELANE (0.81) ELANEKMT2AKDM1AMAPTCA2
SCHEMBL13845250 0.82 ELANE (0.53) ELANEKMT2AKDM1AALDH1A1KDM4E
SCHEMBL4065940 0.82 ELANE (0.53) ELANEKMT2AKDM1AALDH1A1KDM4E
SCHEMBL13845249 0.82 ELANE (0.53) ELANEKMT2AKDM1AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed