Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061370 | 0.88 | ELANE (0.81) | ELANEKDM1ACA2KMT2AMAPT | |
| SCHEMBL2761992 | 0.87 | ELANE (0.64) | ELANEKDM1ACA2OGASMN1; SMN2 | |
| SCHEMBL220773 | 0.86 | ELANE (0.62) | ELANEKDM1ACA2OGASMN1; SMN2 | |
| SCHEMBL6606984 | 0.86 | ELANE (0.62) | ELANEKDM1ACA2OGASMN1; SMN2 | |
| SCHEMBL11371972 | 0.84 | ELANE (0.60) | ELANEKDM1ACA2OGASMN1; SMN2 | |
| SCHEMBL13845252 | 0.83 | ELANE (0.58) | ELANEKDM1ACA2OGASMN1; SMN2 | |
| SCHEMBL4059798 | 0.82 | ELANE (0.72) | ELANEKDM1ACA2KMT2ALMNA | |
| SCHEMBL9341912 | 0.82 | ELANE (0.57) | ELANEKDM1AOGASMN1; SMN2KMT2A | |
| SCHEMBL4928930 | 0.82 | THRB (0.58) | ELANEKDM1ACA2SMN1; SMN2KMT2A | |
| SCHEMBL4057059 | 0.81 | ELANE (0.70) | ELANEKDM1ACA2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |