Sugi Predict

Sugi Predict / Compounds / SCHEMBL2761992

SCHEMBL2761992

SCHEMBL2761992

CC(C)(C)OC(=O)Oc1ccc(C=O)cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 3/20 0.64
▸ KMT2A Q03164 5/20 0.50
▸ ALDH1A1 P00352 6/20 0.47
▸ CYP2A6 P11509 1/20 0.47
▸ KDM1A O60341 1/20 0.47
▸ ALDH1A3 P47895 1/20 0.43
▸ PARP10 Q53GL7 1/20 0.42
▸ PARP3 Q9Y6F1 1/20 0.42
▸ KDM4E B2RXH2 3/20 0.42
▸ MAPT P10636 2/20 0.42
▸ STS P08842 1/20 0.42
▸ OGA O60502 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13845252 0.95 ELANE (0.58) ELANEKMT2AALDH1A1CYP2A6KDM1A
SCHEMBL9313716 0.89 ELANE (0.53) ELANEKMT2AALDH1A1CYP2A6KDM1A
SCHEMBL7708633 0.87 ELANE (0.66) ELANEKMT2AALDH1A1KDM1AKDM4E
SCHEMBL4061370 0.87 ELANE (0.81) ELANEKMT2AKDM1AMAPTCA2
SCHEMBL13845254 0.85 ELANE (0.51) ELANEKMT2AALDH1A1CYP2A6KDM1A
SCHEMBL6606984 0.84 ELANE (0.62) ELANEKMT2AALDH1A1KDM1AKDM4E
SCHEMBL220773 0.84 ELANE (0.62) ELANEKMT2AALDH1A1KDM1AKDM4E
SCHEMBL11371972 0.83 ELANE (0.60) ELANEKMT2AALDH1A1KDM1AKDM4E
SCHEMBL14783590 0.82 KMT2A (0.62) KMT2AALDH1A1CYP2A6ALDH1A3PARP10
SCHEMBL7705620 0.81 ELANE (0.54) ELANEKMT2AALDH1A1KDM1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6461417-B1 Ink compositions XEROX CORPORATION 2002-10-08 — — US claimed
US-6395077-B1 INKS WITH BENZOYLBENZOIC ACID AND COLORS XEROX CORPORATION 2002-05-28 — — US claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 — — US claimed
JP-5262699-A — — None — — JP disclosed
US-20240336617-A1 Substituted Bimane Compounds and Methods of Use Thereof THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2024-10-10 — — US disclosed
CN-114867731-B Dendrimers and derivatives thereof having a thiophosphamide crystal structure 国家科学研究中心 2024-08-16 — — CN disclosed
US-11918656-B2 Antibody-drug-conjugate and its use for the treatment of cancer PIERRE FABRE MEDICAMENT (FR) 2024-03-05 — — US disclosed
CN-117143004-A Chiral aza spiro compound and preparation method and application thereof 安徽农业大学 2023-12-01 — — CN disclosed
US-20230002316-A1 DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS PIERRE FABRE MEDICAMENT (FR) 2023-01-05 — — US disclosed
US-20230002316-A1 DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS PIERRE FABRE MEDICAMENT (FR) 2023-01-05 — — US disclosed
EP-3607996-B1 ANTIBODY-DRUG-CONJUGATE AND ITS USE FOR THE TREATMENT OF CANCER PF MEDICAMENT (FR) 2023-01-04 — — EP disclosed
EP-0525627-A1 Oligomeric compounds containing acid-cleavable protective groups and positive groups and positive-working, radiation-sensitive composition prepared using these cmpounds HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-03 — — EP disclosed
EP-0517428-A1 Poly(para-t-butoxycarbonyl-oxystyrene) and method of making it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-12-09 — — EP disclosed
EP-0498630-A2 Synthesis of para-tert-butoxycarbonyloxystyrene SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-08-12 — — EP disclosed
WO-1992007816-A1 PROCESS FOR PREPARATION OF ALKOXYCARBONYLOXYSTYRENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-14 — — WO disclosed
US-5082965-A Process for preparation of alkoxycarbonyloxystyrene E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-21 — — US disclosed
EP-0102450-B1 RESIST COMPOSITIONS International Business Machines Corporation (US) 1991-09-04 — — EP disclosed
EP-0404206-A2 Resist compositions International Business Machines Corporation (US) 1990-12-27 — — EP disclosed
US-4491628-A TERT-BUTYL ESTERS OR CARBONATES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1985-01-01 — — US disclosed
EP-0102450-A2 Resist compositions International Business Machines Corporation (US) 1984-03-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336617-A1 Substituted Bimane Compounds and Methods of Use Thereof SNCA, PARK7, APP ELANE 166/4885KMT2A 4211/4885ALDH1A1 419/4885
US-20230002316-A1 DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS NR1H4, HCAR3, VDR ELANE 4719/4885KMT2A 4115/4885ALDH1A1 2916/4885
US-11918656-B2 Antibody-drug-conjugate and its use for the treatment of cancer DDOST, DAD1, KRTCAP2 ELANE 3791/4885KMT2A 3496/4885ALDH1A1 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.