Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.57 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | ELAVL3 | Q14576 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | BCL9 | O00512 | 3/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.56 |
| ▸ | POLH | Q9Y253 | 3/20 | 0.56 |
| ▸ | XDH | P47989 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985496 | 0.84 | MEN1 (0.64) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL21139389 | 0.83 | MEN1 (0.54) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL13846134 | 0.82 | POLH (0.58) | MEN1KMT2AKDM4ERECQLHSD17B10 | |
| SCHEMBL13846215 | 0.81 | POLH (0.49) | APPBCL9CTNNB1POLHALOX5 | |
| SCHEMBL28415079 | 0.80 | MEN1 (0.74) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL21139372 | 0.80 | MEN1 (0.50) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL13846136 | 0.79 | POLH (0.66) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL13846223 | 0.78 | POLH (0.65) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| Curcumin SCHEMBL20291461 | 0.78 | MEN1 (0.68) | MEN1KMT2AKDM4ECYP3A4RECQL | |
| SCHEMBL5126336 | 0.77 | MEN1 (0.69) | MEN1KMT2AKDM4ECYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064485-A1 | ANTIOXIDANT FLAVONOID DERIVATIVES | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-05-22 | — | — | WO | disclosed |