Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.68 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.68 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 3/20 | 0.68 |
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA4 | P22748 | 3/20 | 0.68 |
| ▸ | CA7 | P43166 | 3/20 | 0.68 |
| ▸ | XDH | P47989 | 3/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.61 |
| ▸ | APP | P05067 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.61 |
| ▸ | RECQL | P46063 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curcumin SCHEMBL21049944 | 0.95 | MEN1 (0.62) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL8442487 | 0.92 | MEN1 (0.70) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL3715283 | 0.86 | MEN1 (0.93) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL8442485 | 0.84 | POLH (0.64) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29390102 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29377152 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL19235 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL30385934 | 0.82 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL13846231 | 0.81 | POLH (0.59) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL13846131 | 0.81 | POLH (0.53) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3338769-A1 | FORMULATIONS FOR USE IN THE TREATMENT OF ENDOMETRIOSIS AND DISORDERS THEREWITH ASSOCIATED | Inpha Duemila S.r.l. (IT) | 2018-06-27 | — | — | EP | disclosed |