Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 7/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846223 | 0.97 | POLH (0.65) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL13846134 | 0.95 | POLH (0.58) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL13846231 | 0.90 | POLH (0.59) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL13846218 | 0.85 | POLH (0.59) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL13846215 | 0.84 | POLH (0.49) | POLHAPPALOX5BCL9CTNNB1 | |
| SCHEMBL13846131 | 0.82 | POLH (0.53) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL20630211 | 0.81 | POLH (0.67) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL3404530 | 0.81 | AKR1B1 (0.64) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL25304942 | 0.80 | POLH (1.00) | POLHAKR1B1KDM4EPOLBGAA | |
| SCHEMBL30663836 | 0.80 | POLH (1.00) | POLHAKR1B1KDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064485-A1 | ANTIOXIDANT FLAVONOID DERIVATIVES | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-05-22 | — | — | WO | disclosed |