Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 5/20 | 0.59 |
| ▸ | TYR | P14679 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846223 | 0.93 | POLH (0.65) | POLHTYRMEN1KMT2AKDM4E | |
| SCHEMBL13846136 | 0.90 | POLH (0.66) | POLHTYRMEN1KMT2AKDM4E | |
| SCHEMBL13846131 | 0.86 | POLH (0.53) | POLHMEN1KMT2AKDM4EMMP1 | |
| SCHEMBL13846134 | 0.86 | POLH (0.58) | POLHMEN1KMT2AKDM4EMMP1 | |
| SCHEMBL8442485 | 0.83 | POLH (0.64) | POLHMEN1KMT2AKDM4EMMP1 | |
| Curcumin SCHEMBL20291461 | 0.81 | MEN1 (0.68) | POLHTYRMEN1KMT2AKDM4E | |
| SCHEMBL15227652 | 0.80 | POLH (0.58) | POLHTYRMEN1KMT2AKDM4E | |
| SCHEMBL13846218 | 0.80 | POLH (0.59) | POLHTYRMEN1KMT2AKDM4E | |
| Quercetin SCHEMBL8442487 | 0.79 | MEN1 (0.70) | POLHTYRMEN1KMT2AKDM4E | |
| Curcumin SCHEMBL21049944 | 0.77 | MEN1 (0.62) | POLHTYRMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064485-A1 | ANTIOXIDANT FLAVONOID DERIVATIVES | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-05-22 | — | — | WO | disclosed |