Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.46 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383132 | 0.91 | CASR (0.47) | CASRAPPPDK1KDM4ENPSR1 | |
| SCHEMBL1386946 | 0.91 | CASR (0.46) | CASRAPP | |
| SCHEMBL1385726 | 0.91 | CASR (0.46) | CASRAPPPDK1MKNK1ATG4B | |
| SCHEMBL1385344 | 0.90 | CASR (0.54) | CASRAPPPDK1 | |
| SCHEMBL1385543 | 0.89 | CASR (0.54) | CASRMKNK1RIPK1 | |
| SCHEMBL1385867 | 0.81 | CASR (0.59) | CASRAPPKDM4EALDH1A1HTT | |
| SCHEMBL1383335 | 0.81 | CASR (0.54) | CASRRIPK1 | |
| SCHEMBL1385738 | 0.81 | CASR (0.46) | CASRAPP | |
| SCHEMBL1383382 | 0.81 | CASR (0.46) | CASRAPP | |
| SCHEMBL1383579 | 0.81 | CASR (0.55) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |