Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1386100 | 0.94 | CASR (0.56) | CASRTHRBRXFP1RIPK1APP | |
| SCHEMBL1385847 | 0.94 | CASR (0.55) | CASRTHRBRIPK1 | |
| SCHEMBL1385344 | 0.92 | CASR (0.54) | CASRTHRBRXFP1APP | |
| SCHEMBL1383335 | 0.92 | CASR (0.54) | CASRTHRBRXFP1RIPK1 | |
| SCHEMBL1386625 | 0.92 | CASR (0.59) | CASRTHRBRIPK1MAPT | |
| SCHEMBL1383373 | 0.91 | CASR (0.55) | CASRTHRBRXFP1 | |
| SCHEMBL1383579 | 0.91 | CASR (0.55) | CASRTHRBRXFP1 | |
| SCHEMBL1384253 | 0.87 | CASR (0.51) | CASRTHRBKDM4EALDH1A1HTT | |
| SCHEMBL1384191 | 0.85 | CASR (0.55) | CASRTHRBRXFP1ALDH1A1MAPT | |
| SCHEMBL1383223 | 0.83 | CASR (0.48) | CASRRIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |