Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1385867 | 0.91 | CASR (0.59) | CASRRXFP1THRB | |
| SCHEMBL1385344 | 0.91 | CASR (0.54) | CASRRXFP1THRB | |
| SCHEMBL1383335 | 0.91 | CASR (0.54) | CASRRXFP1THRB | |
| SCHEMBL1386100 | 0.86 | CASR (0.56) | CASRRXFP1THRBACKR3 | |
| SCHEMBL1385847 | 0.85 | CASR (0.55) | CASRTHRB | |
| SCHEMBL1386625 | 0.84 | CASR (0.59) | CASRTHRB | |
| SCHEMBL1384253 | 0.84 | CASR (0.51) | CASRTHRB | |
| SCHEMBL1383373 | 0.83 | CASR (0.55) | CASRRXFP1THRB | |
| SCHEMBL1383132 | 0.81 | CASR (0.47) | CASR | |
| SCHEMBL1384720 | 0.81 | CASR (0.46) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |