Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 8/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383132 | 0.91 | CASR (0.47) | CASRAPP | |
| SCHEMBL1384720 | 0.91 | CASR (0.46) | CASRAPP | |
| SCHEMBL1385738 | 0.91 | CASR (0.46) | CASRSIGMAR1TMEM97APP | |
| SCHEMBL1385726 | 0.91 | CASR (0.46) | CASRSIGMAR1TMEM97APP | |
| SCHEMBL1384555 | 0.90 | EPAS1 (0.37) | CASREPAS1 | |
| SCHEMBL1385344 | 0.90 | CASR (0.54) | CASRAPP | |
| SCHEMBL1385543 | 0.89 | CASR (0.54) | CASRPDE5A | |
| SCHEMBL1386007 | 0.84 | MEN1 (0.42) | CASRCNR1 | |
| SCHEMBL1385867 | 0.81 | CASR (0.59) | CASRAPP | |
| SCHEMBL1383335 | 0.81 | CASR (0.54) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |