Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846986 | 0.89 | PNP (0.34) | PNPMAPT | |
| SCHEMBL3990229 | 0.85 | PNP (0.39) | PNPMAPT | |
| SCHEMBL13847182 | 0.79 | PNP (0.30) | PNP | |
| SCHEMBL13846987 | 0.69 | PDE5A (0.32) | PNP | |
| SCHEMBL13847106 | 0.67 | PNP (0.53) | PNP | |
| SCHEMBL3989838 | 0.65 | PNP (0.39) | PNPMAPT | |
| SCHEMBL3365046 | 0.65 | PNP (0.54) | PNP | |
| SCHEMBL3365040 | 0.65 | PNP (0.54) | PNP | |
| SCHEMBL13523344 | 0.64 | ADORA3 (0.48) | PNP | |
| SCHEMBL13847074 | 0.64 | PNP (0.34) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534767-B2 | C-purine nucleoside analogs as inhibitors of RNA-dependent RNA viral polymerase | MERCK & CO., INC. (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080021047-A1 | C-Purine Nucleoside Analogs As Inhibitors Of Rna-Dependent Rna Viral Polymerase | MERCK SHARP & DOHME LLC | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021047-A1 | C-Purine Nucleoside Analogs As Inhibitors Of Rna-Dependent Rna Viral Polymerase | NSUN2, PNP, RNGTT | PNP 2/4885MAPT 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.