Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.49 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848260 | 0.91 | ALDH1A1 (0.47) | PARP14PGAM1GAAALDH1A1HTT | |
| SCHEMBL13848259 | 0.84 | PARP14 (0.48) | PARP14PGAM1GAAALDH1A1HTT | |
| SCHEMBL13848087 | 0.82 | L3MBTL1 (0.59) | PARP14PGAM1GAAALDH1A1HTT | |
| SCHEMBL13848277 | 0.81 | PARP14 (0.46) | PARP14PGAM1HSD17B10ALOX5APFEN1 | |
| SCHEMBL13848251 | 0.80 | PTGES2 (0.53) | PARP14GAAALDH1A1HTTHSD17B10 | |
| SCHEMBL8170997 | 0.79 | L3MBTL1 (0.62) | PARP14PGAM1GAAALOX5APFEN1 | |
| SCHEMBL28215783 | 0.77 | PARP14 (0.52) | PARP14PGAM1GAAALDH1A1HTT | |
| SCHEMBL13848332 | 0.77 | PGAM1 (0.46) | PGAM1GAAALDH1A1HTTHSD17B10 | |
| SCHEMBL13848086 | 0.76 | ALDH1A1 (0.69) | PGAM1GAAALDH1A1HTTHSD17B10 | |
| SCHEMBL13848258 | 0.75 | PGAM1 (0.56) | PGAM1GAAALDH1A1HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |