Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848092 | 0.90 | ALDH1A1 (0.55) | BRD4HSP90AA1HSP90B1TRAP1HPGD | |
| SCHEMBL13848426 | 0.82 | HSP90AA1 (0.60) | BRD4HSP90AA1HSP90B1TRAP1ALDH1A1 | |
| SCHEMBL4544124 | 0.81 | CYP17A1 (0.48) | BRD4HPGDALDH1A1PTGER1KMT2A | |
| SCHEMBL13848259 | 0.81 | PARP14 (0.48) | HSP90AA1HSP90B1TRAP1HPGDALDH1A1 | |
| SCHEMBL13848302 | 0.76 | ALDH1A1 (0.58) | HSP90AA1ALDH1A1NPC1KMT2AHSD17B10 | |
| SCHEMBL8956206 | 0.73 | KMT2A (0.55) | BRD4HPGDALDH1A1NPC1KMT2A | |
| SCHEMBL13848251 | 0.73 | PTGES2 (0.53) | BRD4HSP90AA1HPGDALDH1A1NPC1 | |
| SCHEMBL13848077 | 0.72 | CYP17A1 (0.49) | BRD4ALDH1A1PTGER1NPC1GAA | |
| SCHEMBL21363250 | 0.72 | HSP90AA1 (0.64) | HSP90AA1HPGDALDH1A1HSD17B10GAA | |
| SCHEMBL633995 | 0.69 | KMT2A (0.76) | HPGDALDH1A1KMT2AHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |