Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029121 | 0.85 | QPCT (0.41) | NTRK1CHRM3ALDH1A1LMNAMAPT | |
| SCHEMBL9979540 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HTTLMNAMAPT | |
| SCHEMBL14578376 | 0.81 | ALDH1A1 (0.43) | NTRK1ALDH1A1L3MBTL1HTTLMNA | |
| SCHEMBL14578334 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1HTTLMNAMAPT | |
| SCHEMBL12393705 | 0.81 | ATM (0.62) | NTRK1CHRM3ALDH1A1L3MBTL1HTT | |
| SCHEMBL4023977 | 0.80 | CHRM3 (0.50) | NTRK1CHRM3ALDH1A1LMNAMAPT | |
| SCHEMBL9979656 | 0.80 | HPGD (0.59) | ALDH1A1HTTLMNAMAPTKDM4E | |
| SCHEMBL14578409 | 0.78 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1HTTLMNAMAPT | |
| SCHEMBL6029148 | 0.77 | POLQ (0.43) | NTRK1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL20875262 | 0.76 | NTRK1 (0.52) | NTRK1CHRM3ALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | disclosed |