Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578334 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL14578332 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL14578390 | 0.86 | NTRK1 (0.41) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL9979721 | 0.83 | ATM (0.55) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL14578376 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL13848814 | 0.81 | NTRK1 (0.53) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL14578409 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL14578387 | 0.76 | TDP1 (0.69) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL5111904 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL5111902 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305292-B1 | BIPHENYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |
| US-7176228-B2 | Pyrazole biphenylcarboxamides | BAYER CROPSCIENCE AG (DE) | 2007-02-13 | — | — | US | disclosed |