SCHEMBL138492

SCHEMBL138492

C#CCc1cc(CO)cc(CO)c1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.42
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CASP6 P55212 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3689366 0.81 ENPP2 (0.45) TSHR
SCHEMBL3694910 0.79 TSHR (0.43) ACHEALDH1A1TSHR
SCHEMBL63159 0.76 ACHE (0.62) ACHEKDM4ECASP6TSHR
SCHEMBL14012242 0.75 ACHE (0.39) ACHEALDH1A1KDM4ECASP6
SCHEMBL11201018 0.75 SHBG (0.34)
SCHEMBL208982 0.74 KDM4E (0.43) ACHEKDM4ECASP6TSHR
SCHEMBL18095925 0.74 ACHE (0.42) ACHEKDM4ECASP6TSHR
SCHEMBL9350384 0.70 MEN1 (0.41) ALDH1A1TSHR
SCHEMBL105466 0.70 GSTP1 (0.46) ACHEALDH1A1KDM4ETSHR
SCHEMBL8589719 0.68 ACHE (0.42) ACHEKDM4ECASP6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4742904-A1 CONJUGATES OF ANTIMICROBIAL AGENT AND A LINKER MOIETY SUITABLE FOR COVALENT ATTACHMENT TO MATERIALS AND SUBSTRATES Amicoat AS (NO) 2026-05-20 EP disclosed
WO-2025016913-A1 CONJUGATES OF ANTIMICROBIAL AGENT AND A LINKER MOIETY SUITABLE FOR COVALENT ATTACHMENT TO MATERIALS AND SUBSTRATES AMICOAT AS (NO) 2025-01-23 WO disclosed
US-20120059173-A1 DENDRITIC MOLECULES THE UNIVERSITY OF QUEENSLAND (AU) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059173-A1 DENDRITIC MOLECULES CD40LG, CD40, TLR3 ACHE 4490/4885ALDH1A1 3696/4885KDM4E 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.