SCHEMBL13849561

SCHEMBL13849561

O=C(O)C1C2CCC(O2)C1C(=O)OC(CF)C(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPM1B O75688 3/20 0.51
PTPN1 P18031 3/20 0.51
PPP1CC P36873 3/20 0.51
TFPI2 P48307 6/20 0.50
LMNA P02545 4/20 0.50
KDM4E B2RXH2 2/20 0.50
GMNN O75496 1/20 0.50
PMP22 Q01453 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
THPO P40225 1/20 0.50
PPP1CA P62136 1/20 0.37
PPP5C P53041 2/20 0.36
PPP2CA P67775 1/20 0.36
NPY4R P50391 1/20 0.36
ALDH1A1 P00352 1/20 0.36
FPR1 P21462 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13849562 0.87 PPM1B (0.54) PPM1BPTPN1PPP1CC
SCHEMBL13849564 0.82 PPM1B (0.34) PPM1BPTPN1PPP1CCTFPI2LMNA
SCHEMBL13849565 0.79 PPM1B (0.32) PPM1BPTPN1PPP1CC
SCHEMBL13849604 0.79 TAAR1 (0.35) LMNAKDM4ETSHRALDH1A1HTT
SCHEMBL11991787 0.78 PPM1B (0.53) PPM1BPTPN1PPP1CCTFPI2LMNA
SCHEMBL10280256 0.74 PPM1B (0.64) PPM1BPTPN1PPP1CCTFPI2LMNA
SCHEMBL16250464 0.73 PPM1B (0.45) PPM1BPTPN1PPP1CCTFPI2LMNA
SCHEMBL16731307 0.73 PPM1B (0.62) PPM1BPTPN1PPP1CCTFPI2LMNA
SCHEMBL13704684 0.72 PPM1B (0.47) PPM1BPTPN1PPP1CCTFPI2LMNA
SCHEMBL3497096 0.71 TFPI2 (0.74) PPM1BPTPN1PPP1CCTFPI2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527912-B2 Photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-05-05 US disclosed
US-20080085469-A1 Novel photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. 2008-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080085469-A1 Novel photoacid generators, resist compositions, and patterning process RER1, SCO2, ASIC3 PPM1B 3930/4885PTPN1 3359/4885PPP1CC 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.