Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849750 | 0.84 | MAPT (0.49) | GAAMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL13846438 | 0.84 | NFE2L2 (0.41) | GAAMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL7521076 | 0.74 | MDM4 (0.54) | MEN1MAPK1KMT2AMAPTPOLB | |
| SCHEMBL13846447 | 0.73 | MAPT (0.54) | GAAMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL29230461 | 0.71 | ALDH1A1 (0.53) | MAPK1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13846445 | 0.71 | MAPT (0.59) | GAAMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL401830 | 0.68 | NPC1 (0.57) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5858029 | 0.66 | NR4A1 (0.51) | MEN1KMT2ASMN1; SMN2MAPTCES1 | |
| SCHEMBL5858034 | 0.66 | NR4A1 (0.51) | MEN1KMT2ASMN1; SMN2MAPTCES1 | |
| SCHEMBL13183413 | 0.65 | TSHR (0.50) | GAAMEN1MAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137383-A1 | CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137383-A1 | CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST | CCNT1, SP1, CCNT2 | GAA 2185/4885MEN1 676/4885MAPK1 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.