Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.63 |
| ▸ | NOS2 | P35228 | 6/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | EED | O75530 | 1/20 | 0.54 |
| ▸ | NOS3 | P29474 | 3/20 | 0.54 |
| ▸ | NOS1 | P29475 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | MMP1 | P03956 | 5/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | FCER2 | P06734 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558517 | 0.87 | NOS2 (0.75) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL1558521 | 0.87 | NOS2 (0.75) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL1558519 | 0.87 | NOS2 (0.75) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL1711193 | 0.85 | NOS2 (0.73) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL21996039 | 0.82 | NOS2 (0.75) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL21996040 | 0.82 | NOS2 (0.75) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL21996042 | 0.82 | NOS2 (0.75) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL3168224 | 0.82 | NOS2 (0.67) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL28965792 | 0.82 | NOS2 (0.67) | GRIA1NOS2PPARGNOS3NOS1 | |
| SCHEMBL1711585 | 0.82 | NOS2 (0.67) | GRIA1NOS2PPARGNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | CERNOFINA, LLC | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | SELP, SELE, SELPLG | GRIA1 3301/4885NOS2 1883/4885PPARG 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.