SCHEMBL13853141

SCHEMBL13853141

CCCN1C(=O)N(CCC)C(C)(C)C1=O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.42
PLA2G7 Q13093 2/20 0.38
HTR1A P08908 7/20 0.36
HTR7 P34969 7/20 0.36
HTR6 P50406 7/20 0.36
POLB P06746 1/20 0.33
F2 P00734 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CTRC Q99895 1/20 0.32
CYP19A1 P11511 2/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13853154 0.90 RAB9A (0.51) RAB9APLA2G7HTR1AHTR7HTR6
SCHEMBL13853139 0.89 RAB9A (0.41) RAB9APLA2G7HTR1AHTR7HTR6
SCHEMBL13853150 0.87 RAB9A (0.40) RAB9APLA2G7HTR1AHTR7HTR6
SCHEMBL7040815 0.83 PLA2G7 (0.50) RAB9APLA2G7POLBF2ELANE
SCHEMBL13853140 0.82 RAB9A (0.49) RAB9APLA2G7POLB
SCHEMBL1362555 0.80 RAB9A (0.31) RAB9AF2ELANECTSGCTRC
SCHEMBL13853165 0.80 NPSR1 (0.32) RAB9AF2ELANECTSGCTRC
SCHEMBL7536756 0.78 TP53 (0.38) RAB9APLA2G7HTR1AHTR7HTR6
SCHEMBL13853162 0.78 CYP19A1 (0.32) F2ELANECTSGCTRCCYP19A1
SCHEMBL11389592 0.78 RAB9A (0.38) RAB9APLA2G7HTR1AHTR7HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090121251-A1 Siloxane-hydantoin copolymer, optoelectronic device encapsulated therewith and method LUMINATION LLC 2009-05-14 US disclosed