SCHEMBL13853155

SCHEMBL13853155

CCC(C)N1C(=O)N(CN2C(=O)N(C(C)CC)C(=O)C2(C)C)C(C)(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.39
MARK3 P27448 3/20 0.32
MARK4 Q96L34 1/20 0.32
POLB P06746 1/20 0.31
PKM P14618 1/20 0.30
SIRT5 Q9NXA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13853149 0.92 RAB9A (0.38) RAB9A
SCHEMBL11805450 0.81 RAB9A (0.46) RAB9APOLB
SCHEMBL13853156 0.79 MEN1 (0.33) MARK3MARK4PKMSIRT5
SCHEMBL13853148 0.75 MEN1 (0.32) MARK3MARK4
SCHEMBL13745559 0.69 POLB (0.45) POLBPKMSIRT5
SCHEMBL11843027 0.68 RAB9A (0.54) RAB9APOLB
SCHEMBL11708939 0.67 RAB9A (0.68) RAB9APOLB
SCHEMBL25933853 0.67 ELANE (0.34) PKMSIRT5
SCHEMBL18535425 0.66 ALDH1A1 (0.31) MARK3MARK4PKMSIRT5
SCHEMBL11599601 0.66 RAB9A (0.58) RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090121251-A1 Siloxane-hydantoin copolymer, optoelectronic device encapsulated therewith and method LUMINATION LLC 2009-05-14 US disclosed