Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553669 | 0.92 | PDGFRB (0.74) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3559507 | 0.91 | PDGFRB (0.72) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL13596581 | 0.90 | PDGFRB (0.55) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL13853757 | 0.90 | PDGFRB (0.63) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL13853541 | 0.88 | PDGFRB (0.62) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL15223903 | 0.85 | PDGFRB (0.65) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL13853762 | 0.85 | KDM4E (0.67) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL4369016 | 0.85 | PLA2G4A (0.67) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL1144832 | 0.85 | KDM4E (0.65) | PDGFRBPDGFRAKDM4EALDH1A1HPGD | |
| SCHEMBL15223793 | 0.84 | PDGFRB (0.57) | PDGFRBPDGFRAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118349-A1 | BIS-ALKYLATING AGENTS AND THEIR USE IN CANCER THERAPY | ONCO-PHARMAKON INCORPORATED (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118349-A1 | BIS-ALKYLATING AGENTS AND THEIR USE IN CANCER THERAPY | UNG, MPG, DIMT1 | PDGFRB 4344/4885PDGFRA 4139/4885KDM4E 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.