Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.53 |
| ▸ | F2 | P00734 | 5/20 | 0.53 |
| ▸ | PLAU | P00749 | 5/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13854989 | 0.82 | L3MBTL1 (0.61) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL961818 | 0.82 | ELANE (0.52) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL19236798 | 0.74 | ELANE (0.48) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL12194069 | 0.74 | ELANE (0.56) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL2851292 | 0.74 | L3MBTL1 (0.51) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL3694723 | 0.74 | L3MBTL1 (0.51) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL11146591 | 0.73 | LMNA (0.57) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL4007969 | 0.73 | ELANE (0.45) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL14584150 | 0.72 | CNR2 (0.49) | ELANEF2PLAUCTRB1KLKB1 | |
| SCHEMBL13854988 | 0.72 | ELANE (0.67) | ELANEF2PLAUCTRB1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370784-B | Compound serving as ERK inhibitors | SCHERING CORPORTAION | 2012-10-10 | — | — | CN | disclosed |
| CN-101370784-A | Polycyclic indazole derivatives that are erk inhibitors | SCHERING CORP (US) | 2009-02-18 | — | — | CN | disclosed |