Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 14/20 | 1.00 |
| ▸ | ALPL | P05186 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.80 |
| ▸ | TSHR | P16473 | 4/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | NSD2 | O96028 | 2/20 | 0.80 |
| ▸ | APEX1 | P27695 | 2/20 | 0.80 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | CDC25A | P30304 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683780 | 1.00 | ALPG (1.00) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL18556559 | 0.78 | ALPG (1.00) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL4218138 | 0.76 | TSHR (0.77) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL4208435 | 0.73 | PTGES (0.85) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL4143469 | 0.71 | ALPG (1.00) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL4211375 | 0.70 | ALPG (0.78) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL1528416 | 0.69 | ALPL (1.00) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL4215585 | 0.69 | ALDH1A1 (0.79) | ALPGKDM4EPOLBGAARECQL | |
| SCHEMBL28820656 | 0.69 | GAA (0.58) | ALPGALPLKDM4EPOLBGAA | |
| SCHEMBL4210901 | 0.69 | ALDH1A1 (0.67) | ALPGKDM4EPOLBGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | ALPG 353/4885ALPL 4201/4885KDM4E 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.