SCHEMBL13857095

SCHEMBL13857095

Cc1c(O)cc(O)c2c(=O)c(O)c(-c3ccc(O)c(O)c3)oc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.77
KMT2A Q03164 5/20 0.77
KDM4E B2RXH2 4/20 0.77
ALOX15 P16050 3/20 0.77
MAPT P10636 3/20 0.77
SLCO2B1 O94956 2/20 0.77
ALDH1A1 P00352 2/20 0.77
CYP19A1 P11511 2/20 0.77
HPGD P15428 2/20 0.77
APEX1 P27695 2/20 0.77
DAPK1 P53355 2/20 0.77
FBP1 P09467 2/20 0.77
GLA P06280 1/20 0.77
HSPD1 P10809 1/20 0.77
RAD52 P43351 1/20 0.77
HSPE1 P61604 1/20 0.77
TST Q16762 1/20 0.77
BCL9 O00512 7/20 0.73
CTNNB1 P35222 7/20 0.73
CDK1 P06493 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575800 1.00 MEN1 (0.77) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL6567404 0.87 FBP1 (0.76) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL12640012 0.87 MAPT (0.61) MEN1KMT2AKDM4EALOX15MAPT
Gossypetin SCHEMBL29929428 0.87 MEN1 (1.00) MEN1KMT2AKDM4EALOX15MAPT
Gossypetin SCHEMBL157033 0.87 MEN1 (1.00) MEN1KMT2AKDM4EALOX15MAPT
Gossypetin SCHEMBL29419067 0.87 MEN1 (1.00) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL29962900 0.86 MEN1 (0.64) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL30494621 0.86 MEN1 (0.64) MEN1KMT2AKDM4EALOX15MAPT
Gossypetin SCHEMBL16782915 0.86 MEN1 (0.97) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL4430729 0.83 MEN1 (0.71) MEN1KMT2AKDM4EALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220151274-A1 PREPARATIONS WITH C-METHYL FLAVONOIDS ANALYTICON DISCOVERY GMBH (DE) 2022-05-19 US claimed
EP-3643183-A1 PREPARATIONS WITH C-METHYL FLAVONOIDS Analyticon Discovery GmbH (DE) 2020-04-29 EP claimed
US-20220151274-A1 PREPARATIONS WITH C-METHYL FLAVONOIDS ANALYTICON DISCOVERY GMBH (DE) 2022-05-19 US disclosed
US-20220151274-A1 PREPARATIONS WITH C-METHYL FLAVONOIDS ANALYTICON DISCOVERY GMBH (DE) 2022-05-19 US disclosed
EP-3643183-A1 PREPARATIONS WITH C-METHYL FLAVONOIDS Analyticon Discovery GmbH (DE) 2020-04-29 EP disclosed
CN-109700798-A Chromene flavones structure type androgen receptor antagonists and its application 浙江大学 2019-05-03 CN disclosed
US-20090124688-A1 Prostaglandin reductase inhibitors ABGENOMICS CORPORATION (TW) 2009-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124688-A1 Prostaglandin reductase inhibitors PTGIR, PTGDR, PTGDR2 MEN1 4854/4885KMT2A 3265/4885KDM4E 2123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.