Gossypetin

Gossypetin

SCHEMBL29419067

O=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(O)c(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
KDM4E B2RXH2 4/20 1.00
ALOX15 P16050 3/20 1.00
MAPT P10636 3/20 1.00
FBP1 P09467 2/20 1.00
SLCO2B1 O94956 2/20 1.00
ALDH1A1 P00352 2/20 1.00
CYP19A1 P11511 2/20 1.00
HPGD P15428 2/20 1.00
APEX1 P27695 2/20 1.00
DAPK1 P53355 2/20 1.00
GLA P06280 1/20 1.00
HSPD1 P10809 1/20 1.00
RAD52 P43351 1/20 1.00
HSPE1 P61604 1/20 1.00
TST Q16762 1/20 1.00
BCL9 O00512 7/20 0.73
CTNNB1 P35222 7/20 0.73
CDK1 P06493 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gossypetin SCHEMBL157033 1.00 MEN1 (1.00) MEN1KMT2AKDM4EALOX15MAPT
Gossypetin SCHEMBL29929428 1.00 MEN1 (1.00) MEN1KMT2AKDM4EALOX15MAPT
Gossypetin SCHEMBL16782915 0.98 MEN1 (0.97) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL30190288 0.87 MEN1 (0.77) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL12640014 0.87 MEN1 (0.77) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL20200773 0.87 MEN1 (0.77) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL13857095 0.87 MEN1 (0.77) MEN1KMT2AKDM4EALOX15MAPT
SCHEMBL29575800 0.87 MEN1 (0.77) MEN1KMT2AKDM4EALOX15MAPT
Herbacetin SCHEMBL31442430 0.86 FBP1 (1.00) MEN1KMT2AKDM4EALOX15MAPT
Herbacetin SCHEMBL872691 0.86 FBP1 (1.00) MEN1KMT2AKDM4EALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250364084-A1 METHODS FOR USING A MACHINE LEARNING ALGORITHM FOR OMIC ANALYSIS SEER INC (US) 2025-11-27 US disclosed
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) 2025-11-06 US disclosed
WO-2025038482-A2 USE OF FISETIN FOR REDUCING THE INCIDENCE OF ATRIAL FIBRILLATION RHODE ISLAND HOSPITAL (US) 2025-02-20 WO disclosed
US-20240377411-A1 METHODS FOR DIAGNOSING AN AUTISTIC SPECTRUM DISORDER QATAR UNIVERSITY (QA) 2024-11-14 US disclosed
CN-118488954-A Pyrrolo [2,1-F ] [1,2,4] triazine derivatives as DYRK1A inhibitors 拜斯丽治疗有限公司 2024-08-13 CN disclosed
US-12044684-B2 Methods for diagnosing an autistic spectrum disorder QATAR UNIVERSITY (QA) 2024-07-23 US disclosed
CN-117982428-A Carrier-free co-assembled nanoparticle as well as preparation method and application thereof 沈阳药科大学 2024-05-07 CN disclosed
CN-117883465-A Combination medicine for nerve injury diseases and p38MAPK pathway inhibitor 南京中医药大学 2024-04-16 CN disclosed
WO-2024040189-A1 METHODS FOR USING A MACHINE LEARNING ALGORITHM FOR OMIC ANALYSIS SEER, INC. (US) 2024-02-22 WO disclosed
CN-117398465-A Application of TAB2 protein as rabies treatment target 吉林大学 2024-01-16 CN disclosed
CN-117202924-A Therapeutic regimens and methods for lowering blood glucose and/or body weight using GLP-1R and GCGR balance agonists 斯皮特弗尔制药有限责任公司 2023-12-08 CN disclosed
CN-114957362-B Method for separating anti-inflammatory active ingredients of coreopsis tinctoria 中国科学院西北高原生物研究所 2023-11-10 CN disclosed
WO-2023127826-A1 ELECTROLYTIC CAPACITOR AND LIQUID COMPONENT FOR ELECTROLYTIC CAPACITOR パナソニックIPマネジメント株式会社 2023-07-06 WO disclosed
WO-2023021082-A1 COMPOSITION GIVAUDAN SA (CH) 2023-02-23 WO disclosed
US-20220304974-A1 COMPOSITION COMPRISING GOSSYPETIN FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASE NOVMETAHEALTH CO.,LTD. (KR) 2022-09-29 US disclosed
EP-3970716-A1 COMPOSITION COMPRISING GOSSYPETIN FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASE Novmetahealth Co., Ltd. (KR) 2022-03-23 EP disclosed
CN-114126607-A Composition comprising gossypetin for preventing or treating neurodegenerative diseases 诺代谢健康 2022-03-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220304974-A1 COMPOSITION COMPRISING GOSSYPETIN FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASE HTT, GRN, SNCA MEN1 1130/4885KMT2A 649/4885KDM4E 1427/4885
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM S100A8, TP53, AQP1 MEN1 312/4885KMT2A 4248/4885KDM4E 4766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.