Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.70 |
| ▸ | NMT1 | P30419 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657323 | 0.89 | KCNH2 (0.59) | SIGMAR1KCNH2KCNJ1SLC6A4SLC6A2 | |
| SCHEMBL2326201 | 0.84 | LTA4H (0.64) | SIGMAR1KCNH2SLC6A4LTA4HSLC6A2 | |
| SCHEMBL5754907 | 0.83 | SIGMAR1 (0.70) | SIGMAR1KCNH2KCNJ1SLC6A4SLC6A2 | |
| SCHEMBL5751863 | 0.83 | SIGMAR1 (0.70) | SIGMAR1NMT1KCNH2KCNJ1SLC6A4 | |
| SCHEMBL11630606 | 0.83 | SIGMAR1 (0.70) | SIGMAR1NMT1KCNH2KCNJ1SLC6A4 | |
| SCHEMBL9319743 | 0.83 | SIGMAR1 (0.70) | SIGMAR1NMT1KCNH2KCNJ1SLC6A4 | |
| SCHEMBL15651128 | 0.83 | SIGMAR1 (0.70) | SIGMAR1NMT1KCNH2KCNJ1SLC6A4 | |
| SCHEMBL457139 | 0.82 | SIGMAR1 (1.00) | SIGMAR1LTA4H | |
| SCHEMBL10677264 | 0.82 | SIGMAR1 (1.00) | SIGMAR1LTA4H | |
| SCHEMBL20676401 | 0.81 | SIGMAR1 (0.96) | SIGMAR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158784-A2 | MODULATORS OF THE NUCLEAR HORMONE RECEPTOR ROR | KAMENECKA THEODORE MARK (US) | 2012-11-22 | — | — | WO | disclosed |