Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 2/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13858807 | 0.86 | GSTP1 (0.43) | GSTP1GSTM2KYNUALDH1A1GRM4 | |
| SCHEMBL371150 | 0.84 | GRM4 (0.56) | GSTP1GSTM2KYNUALDH1A1MAPT | |
| SCHEMBL13858853 | 0.84 | CASP1 (0.50) | GSTP1GSTM2KYNUALDH1A1CASP1 | |
| SCHEMBL345271 | 0.81 | GRM8 (0.58) | GSTP1GSTM2KYNUALDH1A1GRM4 | |
| SCHEMBL345272 | 0.81 | GRM8 (0.58) | GSTP1GSTM2KYNUALDH1A1GRM4 | |
| SCHEMBL369315 | 0.79 | GRM4 (0.61) | GSTP1GSTM2KYNUALDH1A1MAPT | |
| SCHEMBL13858835 | 0.77 | KYNU (0.49) | KYNUALDH1A1SIRT2SIRT1SIRT3 | |
| SCHEMBL13858917 | 0.77 | MEN1 (0.51) | KYNUALDH1A1MAPTGAACASP1 | |
| SCHEMBL4092001 | 0.77 | KYNU (0.54) | KYNUALDH1A1SIRT2SIRT1SIRT3 | |
| SCHEMBL4090254 | 0.76 | KYNU (0.53) | KYNUALDH1A1POLBCASP1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212196-B2 | Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof | UNIVERSITE PARIS DESCARTES (FR) | 2015-12-15 | — | — | US | disclosed |
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVWESITE D"AUVERGNE (FR) | 2014-04-17 | — | — | US | disclosed |
| WO-2012156931-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | UNIVERSITE PARIS DESCARTES (FR) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107078-A1 | HYPOPHOSPHOROUS ACID DERIVATIVES HAVING ANTIHYPERALGIC ACTIVITY AND BIOLOGICAL APPLICATIONS THEREOF | HCAR3, HRH3, SSTR3 | GSTP1 2988/4885GSTM2 3651/4885KYNU 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.