Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669778 | 1.00 | PDPK1 (0.40) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL584139 | 1.00 | PDPK1 (0.40) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL13775043 | 1.00 | PDPK1 (0.40) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL7023289 | 0.92 | PDPK1 (0.37) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL584260 | 0.92 | TACR1 (0.38) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL8469404 | 0.91 | LTA4H (0.40) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL25981669 | 0.91 | FGF1 (0.38) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL9058173 | 0.91 | PDPK1 (0.36) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL8831280 | 0.91 | PDPK1 (0.36) | PDPK1MTORSSTR1SSTR2SSTR4 | |
| SCHEMBL8831054 | 0.91 | PDPK1 (0.36) | PDPK1MTORSSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012156750-A1 | HIV VACCINE | ISIS INNOVATION LIMITED (GB) | 2012-11-22 | — | — | WO | disclosed |