Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398371 | 0.92 | REN (0.37) | LTA4HTACR1TDP1L3MBTL1ABCB1 | |
| SCHEMBL8401558 | 0.92 | REN (0.37) | LTA4HTACR1TDP1L3MBTL1ABCB1 | |
| SCHEMBL584139 | 0.91 | PDPK1 (0.40) | TACR1BCHEPDPK1MTORSSTR1 | |
| SCHEMBL13858947 | 0.91 | PDPK1 (0.40) | TACR1BCHEPDPK1MTORSSTR1 | |
| SCHEMBL13775043 | 0.91 | PDPK1 (0.40) | TACR1BCHEPDPK1MTORSSTR1 | |
| SCHEMBL19669778 | 0.91 | PDPK1 (0.40) | TACR1BCHEPDPK1MTORSSTR1 | |
| SCHEMBL8399929 | 0.87 | REN (0.39) | TACR1TDP1NPC1RAB9AKCNA5 | |
| SCHEMBL584260 | 0.86 | TACR1 (0.38) | TACR1NPC1RAB9APDPK1MTOR | |
| SCHEMBL7997389 | 0.86 | SLC5A2 (0.40) | LTA4HTACR1TDP1L3MBTL1SLC5A1 | |
| SCHEMBL7552425 | 0.86 | SLC5A2 (0.40) | LTA4HTACR1TDP1L3MBTL1SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869460-A | ANTIINFLAMMATORY AGENTS | SANWA KAGUKU KENKYUSHO CO., LTD. (JP) | 1999-02-09 | — | — | US | disclosed |