Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.40 |
| ▸ | FNTB | P49356 | 6/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15922647 | 0.84 | KDM4E (0.41) | FNTAFNTBKDM4ELMNAALOX15 | |
| SCHEMBL28911440 | 0.71 | AKR1B1 (0.34) | KDM4ELMNAALOX15RNPEPMAPK1 | |
| SCHEMBL30082456 | 0.71 | AKR1B1 (0.34) | KDM4ELMNAALOX15RNPEPMAPK1 | |
| SCHEMBL3405501 | 0.69 | ALDH1A1 (0.40) | KDM4ERAB9ACHRM3 | |
| SCHEMBL9751048 | 0.67 | KDM4E (0.33) | FNTAFNTBKDM4ELMNAALOX15 | |
| SCHEMBL3379504 | 0.66 | RNPEP (0.47) | FNTAFNTBKDM4ELMNAPKM | |
| SCHEMBL3379508 | 0.66 | RNPEP (0.47) | FNTAFNTBKDM4ELMNAPKM | |
| SCHEMBL3381558 | 0.65 | RNPEP (0.50) | FNTAFNTBKDM4ELMNAPKM | |
| SCHEMBL3381183 | 0.65 | RNPEP (0.50) | FNTAFNTBKDM4ELMNAPKM | |
| SCHEMBL3381561 | 0.65 | RNPEP (0.50) | FNTAFNTBKDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709985-A1 | AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS | Bionomics Limited (AU) | 2014-03-26 | — | — | EP | disclosed |
| WO-2012155199-A1 | AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS | BIONOMICS LIMITED (AU) | 2012-11-22 | — | — | WO | disclosed |