Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953687 | 0.88 | TRPM8 (0.39) | ALDH1A1GLATSHRHTTATM | |
| SCHEMBL15922647 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EMEN1NPC1MITF | |
| SCHEMBL430659 | 0.74 | ALDH1A1 (0.46) | ALDH1A1GLATSHRHTTMEN1 | |
| SCHEMBL430660 | 0.74 | ALDH1A1 (0.46) | ALDH1A1GLATSHRHTTMEN1 | |
| SCHEMBL26327651 | 0.73 | LMNA (0.44) | ALDH1A1GLATSHRHTTOPRM1 | |
| SCHEMBL28958014 | 0.73 | ALDH1A1 (0.48) | ALDH1A1GLATSHRHTTATM | |
| SCHEMBL9324872 | 0.73 | TSHR (0.48) | ALDH1A1GLATSHRMEN1NPC1 | |
| SCHEMBL28571251 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GLATSHRHTTMEN1 | |
| SCHEMBL28958055 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GLATSHRHTTMEN1 | |
| SCHEMBL6550464 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GLATSHRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | claimed |
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | disclosed |