SCHEMBL13860490

SCHEMBL13860490

Cc1cc(-c2cc3c(C)ccc(C)c3o2)c(C)cc1-c1cc2c(C)ccc(C)c2o1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 17/20 0.48
RARA P10276 16/20 0.48
RARG P13631 16/20 0.48
GPR55 Q9Y2T6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13860503 0.87 RARA (0.47) RARBRARARARGGPR55
SCHEMBL13233414 0.81 RARA (0.51) RARBRARARARG
SCHEMBL13860475 0.75 ESR1 (0.39)
SCHEMBL10899283 0.73 RARA (0.46) RARBRARARARG
SCHEMBL12052449 0.73 ALDH1A1 (0.41) RARBRARARARGGPR55
SCHEMBL13743170 0.72 RARA (0.48) RARBRARARARG
Iodide SCHEMBL10901483 0.71 RARA (0.41) RARBRARARARG
SCHEMBL17864585 0.70 RARA (0.39) RARBRARARARGGPR55
SCHEMBL21275688 0.68 RARB (0.65) RARBRARARARG
SCHEMBL21946943 0.67 GPR55 (0.40) RARBRARARARGGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534475-B2 Liquid crystal compound comprising two condensed and substituted rings FUJIFILM CORPORATION (JP) 2009-05-19 US disclosed
US-20070176145-A1 Liquid crystal compound comprising two condensed and substituted rings FUJI PHOTO FILM CO., LTD. (JP) 2007-08-02 US disclosed