Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13860882 | 0.83 | PHLPP2 (0.37) | PTPN11KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13860883 | 0.80 | ENPP2 (0.37) | PTPN11KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13860864 | 0.80 | PTPN11 (0.44) | PTPN11KMT2AMEN1ENPP2GLO1 | |
| SCHEMBL13615157 | 0.78 | ENPP2 (0.45) | THRBPTPN11KMT2AMEN1ENPP2 | |
| SCHEMBL13286618 | 0.77 | ENPP2 (0.43) | THRBPTPN11KMT2AMEN1MAPT | |
| SCHEMBL14029011 | 0.77 | ENPP2 (0.43) | THRBPTPN11KMT2AMEN1MAPT | |
| SCHEMBL13860874 | 0.77 | ENPP2 (0.42) | PTPN11KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL13860879 | 0.76 | PHLPP2 (0.47) | THRBPTPN11KMT2AMEN1MAPT | |
| SCHEMBL14339491 | 0.76 | ENPP2 (0.36) | PTPN11KMT2AMEN1MAPTMAPK1 | |
| SCHEMBL13809222 | 0.74 | CTRB1 (0.38) | THRBPTPN11KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527862-B2 | Dyes for anisotropic dye films, dye compositions for anisotropic dye films, anisotropic dye films and polarizing elements | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-05-05 | — | — | US | disclosed |