Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677 | 0.90 | MEN1 (0.95) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| Hydrochloric Acid SCHEMBL6552954 | 0.88 | MEN1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| Propane SCHEMBL8097570 | 0.86 | MEN1 (0.88) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL22331586 | 0.84 | MEN1 (0.84) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL680531 | 0.84 | L3MBTL1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL18753914 | 0.82 | L3MBTL1 (0.81) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL25819935 | 0.82 | MEN1 (0.62) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL13459322 | 0.82 | MEN1 (0.62) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL15766433 | 0.82 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 | |
| SCHEMBL9149422 | 0.82 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058216-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2009-05-07 | — | — | WO | disclosed |