Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.88 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677 | 0.96 | MEN1 (0.95) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| Hydrochloric Acid SCHEMBL6552954 | 0.93 | MEN1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL8091034 | 0.90 | MEN1 (0.78) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL22331586 | 0.89 | MEN1 (0.84) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL680531 | 0.89 | L3MBTL1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL18753914 | 0.88 | L3MBTL1 (0.81) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL920070 | 0.87 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL19391367 | 0.87 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL15766433 | 0.87 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM | |
| SCHEMBL5911099 | 0.87 | SIGMAR1 (1.00) | MEN1KMT2AL3MBTL1SIGMAR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057371-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS, DRUG ABUSE, ANGINA, MIGRAINE, HYPERTENSION AND DEPRESSION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | disclosed |