Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415440 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1TAAR1HDAC8 | |
| SCHEMBL50012 | 0.85 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1HDAC8LMNA | |
| SCHEMBL1647493 | 0.85 | ALDH1A1 (0.65) | ALDH1A1TSHRTDP1HDAC8LMNA | |
| SCHEMBL3624228 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1TAAR1CA1CA2 | |
| SCHEMBL1140696 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8LMNA | |
| SCHEMBL177912 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8POLB | |
| SCHEMBL1900855 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1HDAC8LMNA | |
| Hydrochloric Acid SCHEMBL3630230 | 0.79 | BLM (0.52) | ALDH1A1TDP1TAAR1KMT2AMAOB | |
| Bromide SCHEMBL11252749 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1TAAR1CA1CA2 | |
| SCHEMBL5149729 | 0.79 | TAAR1 (0.48) | ALDH1A1TSHRTDP1TAAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |
| WO-2009062288-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-22 | — | — | WO | disclosed |