Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9552986 | 0.90 | MAOB (0.52) | TAAR1MAOBHRH3 | |
| SCHEMBL9553164 | 0.90 | MAOB (0.52) | TAAR1MAOBHRH3 | |
| SCHEMBL129246 | 0.87 | TAAR1 (0.67) | TAAR1L3MBTL1MAOBLOXL2 | |
| SCHEMBL14769301 | 0.87 | LOXL2 (0.57) | TAAR1GFERHRH3LOXL2 | |
| SCHEMBL4037603 | 0.85 | TAAR1 (0.64) | TAAR1CYP1A2CYP2A6ALDH1A1L3MBTL1 | |
| SCHEMBL11306666 | 0.85 | ESR1 (0.68) | TAAR1ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL10157930 | 0.85 | TAAR1 (0.64) | TAAR1HTR2ACYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL5511632 | 0.85 | GFER (0.68) | TAAR1GFERHTR2ACYP1A2CYP2A6 | |
| SCHEMBL18087084 | 0.85 | GFER (0.68) | TAAR1GFERHTR2ACYP1A2CYP2A6 | |
| SCHEMBL13960536 | 0.85 | TAAR1 (0.64) | TAAR1CYP2A6HTR3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-01-21 | — | — | US | disclosed |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-01-21 | — | — | US | disclosed |
| EP-3126545-A2 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | The Trustees of Princeton University (US) | 2017-02-08 | — | — | EP | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| WO-2015153381-A2 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-10-08 | — | — | WO | disclosed |
| WO-2015153381-A2 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2015-10-08 | — | — | WO | disclosed |
| US-8288058-B2 | Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode | MITSUI CHEMICALS, INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| EP-1788649-B1 | BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE | MITSUI CHEMICALS INC (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-20070292733-A1 | Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode | MITSUI CHEMICALS, INC. (JP) | 2007-12-20 | — | — | US | disclosed |
| EP-1788649-A1 | BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE | Mitsui Chemicals, Inc. (JP) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022185-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | TAAR1 3219/4885GFER 301/4885ESR1 948/4885 |
| US-10538509-B2 | Decarboxylative cross-coupling and applications thereof | PPOX, DDC, DDO | TAAR1 3614/4885GFER 389/4885ESR1 722/4885 |
| US-20200148668-A1 | DECARBOXYLATIVE CROSS-COUPLING AND APPLICATIONS THEREOF | PPOX, DDO, DDC | TAAR1 3219/4885GFER 301/4885ESR1 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.